Restricted Replication of Xenotropic Murine Leukemia Virus-Related Virus in Pigtailed Macaques
نویسندگان
چکیده
منابع مشابه
Xenotropic Murine leukemia virus-related virus (XMRV) in Iranian HIV Patients
Background: Despite of isolation of Xenotropic murine leukaemia virus-related virus (XMRV) from the patients acquired prostate cancer in 2006 and patients with chronic fatigue syndrome in 2009, there have been controversial findings about its potential role in human diseases and frequencies in different population groups. In the present study, we aimed to determine the frequency of XMRV genome ...
متن کاملThe tale of xenotropic murine leukemia virus-related virus.
In 2006, a new retrovirus was isolated from prostate cancer patient tissue. Named xenotropic murine leukemia virus-related virus (XMRV), this was potentially the third class of retrovirus to be pathogenic in humans. XMRV made a more dramatic impact on the wider scientific community, and indeed the media, in 2009 when it was reported to be present in a remarkably high proportion of patients with...
متن کاملAndrogen stimulates transcription and replication of xenotropic murine leukemia virus-related virus.
Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus originally identified in a subset of prostate cancer patients. Because androgens stimulate prostate tumors and some retroviruses, we investigated the effects of dihydrotestosterone (DHT) on XMRV transcription and replication. Transcription from the XMRV U3 region was stimulated up to 2-fold by DHT, but only in cells cont...
متن کاملXenotropic Murine Leukemia Virus–related Gammaretrovirus in Respiratory Tract
Xenotropic murine leukemia virus-related gammaretrovirus (XMRV) has been recently associated with prostate cancer and chronic fatigue syndrome. To identify nucleic acid sequences, we examined respiratory secretions by using PCR. XMRV-specific sequences were detected in 2%-3% of samples from 168 immunocompetent carriers and approximately 10% of samples from 161 immunocompromised patients.
متن کاملXenotropic and Other Murine Leukemia Virus-Related Viruses in Humans
1 Laboratory of Retroviruses, Division of Viral Products, Center for Biologics Research and Review, US Food and Drug Administration, Bethesda, MD 20892, USA 2 Jefferiss Research Trust Laboratories, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, Norfolk, London W2 1PG, UK 3Department of AIDS Research, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2012
ISSN: 0022-538X
DOI: 10.1128/jvi.06886-11